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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '727028da11099b756152eb97cbe2c4d885a94637ac56fe6523cc8263564969f9' 
  AND token = '/tZkIpxoLke9pTOINjvbqRXCOMMoT8BDa2jbu/Fscl0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}