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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e5226bb9685bf312f5b9eaf58b1e38d4c0157207bb1b9b24a4d0e6abaf5ec49' 
  AND token = 'xZdIAQ+KKs9HdmPIxFr6Wx8k3eid0E4K7v5m3h4KRuI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}