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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3353fe7e4f1cbb0d77ccaaa4c6f791f454462e734cfb8642b14a00d868b91bff' 
  AND token = 'z/r1TQ+luTU2PKFLBgSNt2/yhr+NvU5SNTzPPPSD6uE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}