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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd50aa77df863956ba167bf5ac5d2d07f78515cd0ebc8f9a8a6038882ab606218' 
  AND token = 'D6Sgx1a28YQ40yovf3m9GN9YoA9Ey+LBBjRrCT63Nnk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}