SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd6b965b5e8d4f42956b8edb99974864550b14475c4ba4112ca6e0aef1da9aa5' 
  AND token = 'ydOp2gElTn2jld7eZ3F8VG/jPrDW0yh2mQLISfd+/Gk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}