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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cab3f1d6b80ecc019cdde1fccb2b4b45a7ad63d3ac0e957388a937a128e445d' 
  AND token = 'E+bd7c4q8yfDqjukRJ8Y3TU5uzDuxaJ4ieO5XuLguU4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}