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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '98880c0786af3ade310c0bf0bf51a8aec16ea9399e907c88abf46c72706dc5c0' 
  AND token = '+P7mzYCbW0H2FEhjmMKF8CLW7fmQhcJ2MtlpXSJvJ8I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}