SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4d6ed68b7f90345b6eddb995d89661d3fc7d5689d7bbde7a56b6220b3036984' 
  AND token = 'X/BsEfhktoBBRMw6xcTJ1u2bdiJdAwFvtcOXAY+ADFI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}