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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd49974f6b6dffb3a171404c6bc7b68e2bff44c0cd5b606490ce8544dcbbccb9a' 
  AND token = 'LBxSlHBVFhvlWLD4ZapbTjsr9jbsp+Sy3fwAFWrCRJA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}