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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '222a5c78bba132aba17e8b9effcd5fe5387da8383677b5f289827d7b9650f4c8' 
  AND token = 'ArQKd0pm1ZzNEojzxi8cAd4fK1GpY4imEf7rhYbCjmw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}