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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ca328fd4c772903b705229d263e92f3ec42c3f6a3b4173cd3285df7de593a12' 
  AND token = 'my6Gb6Zy+G1SMfy4nqy2/l7yCg6Qd1Qlp4mFpTBnMKE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}