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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8877033d9bab710f9187b0db72ad8fc9c7f6f110ca22267b95e1bccea2604779' 
  AND token = '6s2fVceZKyfM6IxbvOwfybhtPERDA+NBifwiMrtiO3Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}