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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d20f15189c8d8e715f365ae30705fe45099bf292f3b42e21eb629fadce3c72d' 
  AND token = 'qQVyiYwy8hRzLoJjzP1T4/8iZZ9cCzSZfT2u16R5pJw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}