SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '325fbe6e30dc614916b11d88f9e9a50ebfdb037a4cc8bcc60cc59f722262e329' 
  AND token = '3C1eM4s/t8by7XfmLcfbHinypxUbGBcJ2xn9yCFMrRc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}