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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '590e8fca9a2dcd54413e35025303d6c956fe794f65501a1b728198d0e26f45ca' 
  AND token = 'SDjm5ab3TTU5/V9n0JLeaNrtqAZ8KncBIrJ5dvWGLEs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}