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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6b7571b72819e5bec337a5d5fee9eaebcdc995c35341129b3099beebe628525' 
  AND token = 'qvauBBOj2vsD+IP4usxxbDubhoum3nvRrxABxSGuqII=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}