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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dda67a9bbd5c64eeaef85222938cbeaf78e015e93c6c87c876c678be6d8d89be' 
  AND token = 'E4c4PHavOnbM+mhw1FmJZiOmz9g6EW348+TtJx7T6RQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}