SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0dd091df81cefd0afc40c993a5b5cb12c33571a01a1c9cc138e1738dfd6c3e41' 
  AND token = 'y2Qazp0cxcLoJ7opD3s+FWkNKwGrhEAtUtZWebVXQ70=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}