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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c988e6e178c0795cc864533ea7a933f20173f8f6f1dc7edf6b628077b3cb201' 
  AND token = 'dfloYLf8/+A8UpqjoddTTfwnzoBYY9RcBAjwo/uSIiA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}