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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d0ba79bcca1efa1dcf3222041d9a640fa670030bf449334b183a1fc9c4f0de2' 
  AND token = '78ootmgnzkeyQhvJGzr4jMSJcRW7c7PJQKbTa4pCJeU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}