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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c74b9d62bc6959f7942835e26eed85785c0d95774472e8d37217642faef7a9b' 
  AND token = '8dUs4Xpthc3SffZd/2kj+osIJf1fmwpjLFgoHdOBckE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}