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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d76b81e492d81d934055a80a77e22b26a9995fe3e1ab48f2054bc4255607210' 
  AND token = '1MUmJMr+3/zdSrcVEErxPYpGel2WH5OoYCPgRV1Ovc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}