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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66e4f279228fc54526b17a5a5defea980e95f13b54da81e7ed0b92241ce02df3' 
  AND token = 'JD92sw3R1IEg4PMY3Tc1sIJXGrDx9ei46I7rX5R0Fzs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}