SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80cbadff894393ea1e1ad88490348f75f81ef3c6b68dea512ee3c17a9e37fb10' 
  AND token = 's6bo8yaayVPc3I89za94UMG17GHW1CR9LWGZGe1YWHY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}