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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2151398e9ff19b783892c6c6b1267218fc4caabd876c78ec010a79df989b664f' 
  AND token = 'JkVx0Cc4zY5xyg6EZ0fBQyH3pjCcR7u+no9rFUxdSYc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}