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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8dee1817e8d8585ee762bf9e8b50f5806cd9fa28d64c8b252b71090cc304469' 
  AND token = 'LtVdXhGr0r6S6p7YNTGsC58AJWVhJ0JjU6Wdz0es4Sg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}