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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86539fcf06dc9d8b7c04fc0d47b251250faf81b0567a3c1ca7508abfe1cad056' 
  AND token = 'lTcF1VBxsx+f0GxmPoCh6jFjiPWrqSxSt27uUsuqVYQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}