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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd41ff3e8a9d7407da34b3010e4c09ff3b7252310e5786bd770d6e4aa6c48af78' 
  AND token = 'zi7bJ65cMD23Kf/onY048MEWpLlNnDQHk7XwkzKt/os=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}