SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '965748500c9ab3ac288ca4a64a21433b63b58a8a1a0e57f5516403a09aae9ec1' 
  AND token = 'tBSdGy4i0SkaFNWm9s68yNkXqAx9At1GKWulPymOEHE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}