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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e78f5dc7fbbb1d7f8cd231587ae1e80183ab10827c875c2deea2e7cab486a76' 
  AND token = 'IcGD6Fmb3Uiw2qdqqRSsLxOspJVO02eNNXviOUtGjaI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}