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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a79397282d0ae5387cb9d29ba11e8773ecb56038bf0e4563721c7acbb598de1' 
  AND token = 'pz7eTRRtG598Ymb2/ls7T3bAfa3u5OXu/5zsnR9Tyh8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}