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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f764b7d162ce938da003ba037f4cc31311bc0f6b210d0dae3ba0915783e2b12' 
  AND token = '9tcPbcqt9GcC5AS1kQrOI2bCq8AID5ZDGR4LWS64Mcw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}