SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05b60161e84f835494383ff26ae901399763f959b91f257aafc3f80be7fbb099' 
  AND token = 'ngKPr8vQ59HzdKaWiSVVLkXVfLv6FYmFdSggEVXJF0Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}