SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd5738dc5fd9ff40bde6ac1cbf6b08f34f1782f9827eac10f3d291700165ef99' 
  AND token = 'N3d/r6+YBcDuJAu2ix0/rj9KFaHHa/EaN2+ipKOaavk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}