SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0357f206e250e162b8ab593e3b8d1068526374d3709950c13f7c42aa66d384d' 
  AND token = '9b0J6tb8CEDQYNK8x2EoQhdfOGAq7WwaIn4Tb/jSZVo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00098

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}