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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1b104c1c15b9ab1a2755d73809b42614e088afab7c12314fe6a7a08868cf47b' 
  AND token = 'zQBh0C3rQ9B+TFdNDD1hpFBBbvKHNk+ur/15mjKWAvA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}