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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b325c1672451eda498dd46742f74f9f2e6bc805340ae41e7722477b92c89e4e' 
  AND token = 'IJXnj10hsPCDAtBev9xPiMCOqSGX3qF56Zj/xHMjLyc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}