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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '47728d16f3aad36b6219c5e214f6cfe3adb407f6b98491eabc82e5b84d389e16' 
  AND token = 'Q1+UqURE21Vn71pf+A/PDwt1/P78SSrOgwnPgsyWtws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}