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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50fe8749d277b564d7b3115f470b5298a68c940974c7e2d9b9ae2389091975e8' 
  AND token = 'lPHAwtGqpKRskXV5h5OpOCCxeao/6Zdr2GTJV0r6V3Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}