SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '327736974aaf48bea3fbdb95aab4f176131ce882d53f8f237189cac8a3b1d8ba' 
  AND token = '/QV0OUF5bGzs3tBoAKpDaRiCd/LbD0GOzw5JKGMg2NA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}