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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4e65bb52815ee8dfe3c94f4b0159ce292ffc63f6d5f743d41346438d727378c' 
  AND token = 'fQjPrtd+0Mp0mnQCDANARAs8QiBaVrtZNzKahqKFAPc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}