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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6649a51cc8007dd5f39a8b08bb85e5cd4fa30bbdc241bc731c982e43ddcc15fc' 
  AND token = 'uKN7Ybcx6JVPKypTUIpnIrrSC6QR54yhZXqKTPJzqO8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}