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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '160e8a59083a007506b5ba1c9cfbc34d3bf87afcbb447773e0972509503b0add' 
  AND token = 'gj5bwi6PnK9SXC72w0oiDe79wVcaYpdvar/DteIQC94=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}