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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e76e4fc1554b30e4becfcdcbdfdbb44c4160cbdf694e3520f66998b2f35d3c08' 
  AND token = 'rqVMtBfJbGLsLtpQWRRh7qn/8sZQAGFXku28gO1dbes=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}