SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c305e2c0499729392ea652ef9d15f3e392b2545c76e418e6c023bc4ff266c9e0' 
  AND token = 'oSn2guCTmFW8cmpGFtay1Gi9vbZM1nkY2wOLR2qqBh8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}