SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '214c7835666f6bdc1bb0ab31c9ec2016c7e6be0975b69fe0c9ce78936afbfe77' 
  AND token = 'Aw/Yti4MI95WlxQDoU9n6YeJ6/ep9L/ONV1XKdMTy4w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}