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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95663e8a0f0bee47b805bfeee7687f63e5a1fff74439ff6d18663e1e1cda9508' 
  AND token = 'bcuILf2PQUB2/voDv5FX9K0RVcxmB7XMunpIiiQV9lA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}