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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18e86d243d1da053cc5a32eb93b2264171573f465f5949622ccc18d53c96d52a' 
  AND token = 'xZ5kmY8ZSFFH1wIZ9MCzpkAt62mhl9dVRPXNM94VUpo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}