SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'addafb8516bd203b57f3506f54edf2cf13dfe0cd24091e23685fa7063a49f220' 
  AND token = 'mR7hVUuz1Kl8KJGgi1+pqUDdPNhOM7Plpho3jaxQGAU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}