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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc946fd80f5220008d0d201617f987c49910a071e99259a840f14bbd8ed43465' 
  AND token = 'alPHWyj8FgeNGoDDj6evSQDMOT2xk+NNr4kaJufjkrc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}